News about rhinoplasty: Let's learn about Malignant Hyperthermia (MH), a silent threat that is passed down genetically.
Regarding the recent news about a patient who underwent rhinoplasty and is still unconscious from anesthesia, I want everyone to understand that "this is not a typical surgical procedure." It's a specific bodily reaction to certain types of anesthesia, occurring in 1 out of 100,000-250,000 cases (this figure only includes cases requiring general anesthesia).
What is Malignant Hyperthermia (MH)?
MH is a condition characterized by a sudden and severe rise in body temperature (high fever exceeding 40 degrees Celsius), severe muscle spasms, and acidosis, resulting from the body's exposure to... "Anesthetic inhalant" หรือ "Muscle relaxants" Some types stimulate abnormal genes in the body.
🧬 Genetics: A topic so close to home that you need to check your last name!
The terrifying thing about this disease is... "Genetic transmission" Yes, it's passed down from grandparents to grandchildren, and the person may never even know they have the condition until they receive anesthesia for the first time in their life.
In Thailand, data from anesthesiologists indicates that there have been reports of individuals at high risk. 14 นามสกุล From now on, if you or a family member uses these surnames, you need to be especially careful.
- Jiuyan
- Tipayakraisorn
- Beautiful Diamond
- Inthep
- Khmer keyboard
- Todd Kaew
- Charoen Dong
- Phothidet
- Mawong
- Sandalwood
- Prangthong
- Onnapa
- Round and rolling
- Oops, noon water.
Another source indicates that there are as many as... 32 นามสกุล (This is a duplicate of the above.)
- Thipkraisorn
- Jiu Yan
- Beautiful Diamond
- Inthep
- Paem Khom
- Mawong
- Charoen Dong
- Bright candle
- Todd Kaew
- Wiwat people
- Prang Thong
- Phothidet
- Sandalwood
- Cheerful mood
- Gentle
- Round and rolling
- Vithan
- farm
- Takkan
- Baworn Wiratkul
- Akrawanichlert
- Relying on the city
- Noon water
- Phlai Thongdee
- Chanthawong
- Banana
- Fisheries
- Intharak
- Dechraksa
- Kongrat
- The tiger is full.
- Rongsanthia
(Note: Other surnames also carry a risk if there is a family history of deaths or adverse reactions during anesthesia.)
💉 The rare antidote "Dantrolene" that you need to know about.
When MH (Myasthenia Gravis) occurs, the only medication that can save lives is... “Dantrolene” Yes, but the point is, this medication is very scarce in Thailand and is usually only available in large hospitals because the incidence of this disease is very low. Many hospitals keep it until it expires without using it, but when the time comes, it's truly a life-saving drug.
🔍 How can I find out if I have MH (Myasthenia Gravis)?
If you are concerned or are in a high-risk group, the doctor recommends the following testing methods.
1. Genetic Testing
- How to test: A blood sample is taken for testing to check for gene abnormalities (the most common being the RYR1 gene).
- The advantages: It doesn't hurt much, just a blood draw.
- Limitations: Genetic testing may not cover all abnormalities 100% (a negative result doesn't mean you don't have it) and is quite expensive.
2. Muscle biopsy (Caffeine Halothane Contracture Test – CHCT)
- How to test: It was a minor surgery to take a tissue sample from the thigh area for testing its reaction to caffeine and anesthetics in the lab.
- The advantages: It is the gold standard method for diagnosis.
- Limitations: A biopsy is required, and there are only a few testing centers in Thailand.
3. Taking a family history (most important!).
- Check to see if any blood relatives have ever experienced abnormally high body temperature, irregular heartbeat, or unexplained death during or after anesthesia.
💡 Advice from the doctor.
Before any surgery, whether minor or cosmetic.
- Inform the anesthesiologist: Provide your last name and detailed family history.
- Choose a medical facility that is well-equipped: If you know you are at risk, you should choose surgery at a hospital that has the necessary equipment and Dantrolene on hand.
- Alternative options: Inform your doctor that you would like to use an alternative to high-risk anesthesia methods, such as local anesthesia or intravenous sedation (TIVA), instead of inhaled anesthetic gas.
Out of concern for everyone's safety and beauty, please remember to check your health history before undergoing any surgery. ❤️
