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For a dewy, glowing complexion, which PN injection is best, doctor?

Since the beginning of 2026, this has been one of the most frequently asked questions I encounter at my clinic: "Which PN injection is best?" Friends and patients alike are scrambling to find information, asking, "Is this brand or that brand any good?"

Speaking as a cosmetic doctor, I can tell you that... "There's no single best product for everyone, but there's one that's best suited to each patient's individual skin problems." Because skin structure, age, and the concerns we're concerned about are different for everyone, even the same PN (Permanent Makeup) type will yield different results depending on the patient's case.

Group of extracts PN (Polynucleotide) Or what we commonly refer to as... Skin Booster (for radiant skin) This is a deep skin rejuvenation process at the DNA level. Each brand has slightly different strengths and sources of DNA. To provide a clearer picture and make it easier to decide, the doctor has created a summary table of 3 options. Rejuran, Vitaran, and NucleoFill Let's compare them side by side.


This information is for informational purposes only and is not intended to recommend any specific innovation/technology. Please schedule an appointment with a doctor for a detailed assessment and advice.

Comparison table of Skin Boosters in the PN group (summarized by a doctor).

ProgramMain extractWho is it suitable for?Key Features & ResultsFrequency & DurationEstimated price range/time*
Rejuran H
(Rejuran)
PN derived from salmon DNA.Do you have problems with acne scars, pitted scars, enlarged pores, or dull skin?Restores and repairs damaged skin, making it stronger, reducing inflammation, and giving the skin a plump, hydrated look.3-4 injections (2-4 weeks apart)
The results last a long time. 6-8 months
9,000 – 15,000.-
(Per 1 syringe, 2cc)
VITARAN I
(Vitaran)
PN derived from salmon trout DNA.Fine lines, enlarged pores, dark circles under the eyes, uneven skin tone.This molecule is ideal for sensitive skin, such as under the eyes. Spraying it all over the face will give you a glass and glow complexion.2-3 injections (3-4 weeks apart)
The results last a long time. 6-12 months
6,900 – 12,000.-
(Per 1 syringe, 2cc)
NucleoFill
(nucleophyll)
PN 2.5% from salmon DNA.I have problems with wrinkles, sagging skin, and very dry, dehydrated skin.have Lifting Effect Helps to lift and firm the skin from within, resulting in plump, firmer skin structure.3-4 injections (3-4 weeks apart)
The results last a long time. 6-12 months
11,000 – 18,000.-
(Per 1 syringe, 2cc)

(  The price depends on the promotions offered by each clinic and the amount of product (in cc) used, which will be assessed based on the patient's skin condition.


💡 Simple summary, doctor's style.

  1. A lifesaver for damaged skin and lots of acne scars: If the patient has redness, dark spots from acne, or skin that has been damaged by chemicals, or is sensitive and in need of intensive repair 👉 They swear This is a legendary product that restores damaged skin to a healthy state.
  2. Dark circles under the eyes? Want radiant, glowing skin? (Glass Skin) If you're particularly concerned about tired-looking under-eyes, fine lines, and want that dewy, radiant Korean skin look 👉 VITARAN Because this product is good for injecting into sensitive areas and effectively reduces inflammation.
  3. The skin starts to age, becoming dry and saggy: If the patient feels their skin is sagging, losing elasticity, dry, and creams don't absorb well, and they want skin rejuvenation and gentle lifting results 👉 NucleoFill  It effectively addresses the challenges of aging.

For noticeable and long-lasting results from a Skin Booster treatment, it's recommended to receive a continuous course of injections initially (approximately 3 times). After that, your skin will become much more hydrated and stronger.

If you're still unsure which product is right for your skin, please feel free to visit our clinic for a real skin assessment. The doctor will be able to analyze your skin and choose the most cost-effective and suitable formula for you. We're happy to help! 💕

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