Exosome Skin Booster revitalizes skin cells for a youthful appearance.

Get ready for the hottest anti-aging program! D' Exosome Baby Skin at D' Lovevery Clinic offers a skin rejuvenation experience using innovative MicroRNA and Exosome technology. This treatment utilizes stem cells to create tiny, highly concentrated particles—over 5 billion cells—to give your skin a youthful, radiant, and hydrated look.

What is an exosome?

Exosomes are nanoparticles that play a crucial role in cell-to-cell communication. They can be found in various bodily fluids such as plasma, serum, saliva, cerebrospinal fluid, urine, and cell culture media. They are composed of biomolecules derived from stem cells, such as nucleic acids, proteins, lipids, and metabolites.

Many people are familiar with beauty innovations like Botox, mesotherapy, fillers, and thread lifts, but the term "exosome" might be new to many, as it's an innovation invented by researchers and experts abroad. Let's explore the benefits of exosomes.

1. Exosomes are a technology composed of very small proteins, measuring 30-100 nm—1/1,000th the size of a typical cell. They have a function that helps regenerate skin beyond the cellular and stem cell levels.
2. Exosomes contain over 1,000 different biomolecules, such as cytokines, growth factors, microRNA, genetic information, and other proteins. They are 1,000 times more effective than PRP.
3. Direct exosome injection allows for more precise treatment, enhancing skin rejuvenation, reducing melasma and dark spots, and stimulating hair growth by up to 200%.

The D' Exosome program delivers excellent and distinctive results.

• Contains up to 6 times the concentration of collagen.
• Boosts skin elasticity by 300%.
• Reduces pigmentation problems, redness, and dark spots.
• Hydrates the skin, making it look plump and hydrated.
• Reduces wrinkles, tightens and smooths the skin.
• Evens out skin tone and brightens complexion.
• Noticeable results can be seen 1-2 weeks after treatment.
• For optimal results, we recommend receiving the service every 3 months for 3 consecutive times (averaging 3-4 times per year).

The working principle of exosomes is to directly transport various biomolecules into cells, using the exosome as an intermediary for communication between cells, similar to sending messages to other cells. The biomolecules delivered via exosomes stimulate processes in skin cells, such as metabolism, fibroblast production for collagen and elastin, and the fight against free radicals that damage skin cells and promote aging.

In addition, exosomes play a role in delivering drug components or therapeutic substances to cells, helping to restore and repair tissue function, such as promoting cell proliferation and wound healing effectively.

In summary, how does Exosome benefit the skin and slow down aging?

It stimulates the regeneration of new skin cells and restores skin cell function, making cells stronger, reducing skin allergies and inflammation, stimulating collagen synthesis in the skin, and making the skin more elastic and firm.
Helps reduce signs of aging and slows down the deterioration of skin cells by stimulating the activity of antioxidants.
Hydrates and plumps the skin, leaving it looking radiant and healthy.

Those who should be treated with Exosome are listed in order of the problems most frequently discussed at D' Lovevery Clinic.

1. A group of patients who want their skin to look younger and to stimulate collagen synthesis.
2. For those who want to relieve allergic and inflamed skin symptoms.
3. The patient wants to improve skin tone and balance pigmentation.
4. Helps in the healing of various wounds.
5. Benefits for psoriasis patients.
6. It helps people with hair thinning due to various reasons, such as genetic factors, health problems, stress, or the use of chemicals in hair dyeing.

What are the differences between Exosome and Rejuran?

Exosome and Rejuran play a different role in skin treatment. Exosome stimulates the regeneration of new skin cells and restores existing cells to their full function, while Rejuran focuses on repairing damaged skin cells, restoring their strength and effectiveness. Both contribute to healthier and more youthful-looking skin.

How should I prepare before getting an Exosome injection?

1. Discontinue taking antiplatelet and anticoagulant medications for at least 3 days prior to treatment.
2. Avoid taking pain relievers containing aspirin for at least 3 days prior to treatment.
3. Discontinue consumption of supplements such as vitamin E, fish oil, and ginkgo biloba extract for at least 3-7 days prior to treatment.
4. Avoid scrubbing or exfoliating your skin before treatment to prevent the risk of adverse reactions.

Self-care after Exosome procedure.

1. Apply a cold compress after treatment to help reduce pain, swelling, and blisters.
2. Avoid scrubbing, exfoliating, peeling, and laser treatments for at least 7 days after treatment.
3. Avoid touching your face or massaging it vigorously after treatment.
4. Refrain from consuming alcohol for at least 3 days after treatment.
5. Avoid activities that expose you to intense sunlight or cause excessive sweating, such as sunbathing, using saunas, diving, and other activities that may irritate your skin.

Research related to Exosomes.

1. Yáñez-Mó, M., Siljander, PR, Andreu, Z., Zavec, AB, Borràs, FE, Buzas, EI, … & De Wever, O. (2015). Biological properties of extracellular vesicles and their physiological functions. Journal of extracellular vesicles, 4(1), 27066. [Link: https://www.tandfonline.com/doi/full/10.3402/jev.v4.27066]
2. Tkach, M., & Théry, C. (2016). Communication by extracellular vesicles: where we are and where we need to go. Cell, 164(6), 1226-1232. [Link: https://www.cell.com/cell/fulltext/S0092-8674(16)30177-0]
3. EL Andaloussi, S., Mäger, I., Breakefield, X.O., & Wood, M.J. (2013). Extracellular vesicles: biology and emerging therapeutic opportunities. Nature Reviews Drug Discovery, 12(5), 347-357. [Link: https://www.nature.com/articles/nrd3978]
4. Kalluri, R., & LeBleu, V. S. (2020). The biology, function, and biomedical applications of exosomes. Science, 367(6478), eaau6977. [Link: https://science.sciencemag.org/content/367/6478/eaau6977]
5. Colombo, M., Raposo, G., & Théry, C. (2014). Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. Annual Review of Cell and Developmental Biology, 30, 255-289. [Link: https://www.annualreviews.org/doi/full/10.1146/annurev-cellbio-101512-122326]